Myoepithelial carcinoma arising in a benign myoepithelioma of the palate. Case report and literature review

Myoepithelial carcinomas are tumors arising from myoepithelial cells mainly or exclusively, they showed varied cell types and patterns leading to a wide range of differential diagnoses. Immunohistochemical analysis helped to determine the diagnosis. Recognition of myoepithelial carcinoma is clinically significant because, compared to its benign counterpart (myoepithelioma), It has increased frequency of local recurrences and metastases, which warrants close clinical follow-up. The aim of this case report was to present a rare neoplasm, myoepithelial carcinoma arising from a benign myoepithelioma of the palate, and to review its diagnostic criteria, pathologic and clinical characteristics, treatment options and prognosis.